In view of global climate changes, the study of the ecological feasibility of hydromelioration systems and their impact on the natural environment is extremely relevant. Evaluation of the ecological effectiveness of water regulation of drained land for current and forecasted climatic conditions was performed by determining the environmental reliability coefficient, which characterizes the ecological reliability of a reclamation project. The environmental reliability coefficient was determined on the basis of a certain set of physical indicators. The set of physical indicators reflects the extremely complex nature of the formation of water and general natural and ameliorative regimes of reclaimed land as a whole in changing natural, climatic and agro-ameliorative conditions of real objects. Their determining is based on the implementation of a machine experiment based on a complex of predictive and simulation models for water regulation of drained land on a long-term basis. The obtained results showed that ecologically optimal natural, ameliorative and soil regimes of the drained land, subject to compliance with the restrictions , are ensured by the application of humidifying sluicing. At the same time, the environmental reliability coefficients are 0.59 and 0.58, respectively, for current and forecast climatic conditions, and the level of ecological reliability of applying humidification to drained land is sufficiently high. The carried out evaluation of ecological reliability of water regulation of drained land confirms the need to increase the role of humidification as a component of effective adaptive measures on drained land in modern and forecasted climatic conditions. Humidifying measures have a decisive influence on the ecological effect and the ecological and amelioration state of drained land.