Wastewater contamination which causes health, environmental and economic impacts is one of the most common environmental issues. Several methods have been used for the upgrade of the existing wastewater treatment facilities, nevertheless, the application of phytoremediation treatment is a promising and environmentally friendly method to avoid the secondary contaminations posed by the treatment dosage in other advanced treatment methods. The current work aimed to assess the phytoremediation treatment of the pre-treated domestic wastewater using the Salvinia molesta and water hyacinth plants. The water quality tests were performed in the current research to evaluate the effects of the phytoremediation treatment using the Salvinia molesta and water hyacinth plants on the responses of the water quality parameters. The study focused on varying two main parameters, namely the pH and the hydraulic retention time (HRT), while the removal rate was determined based on the reduction in the chemical oxygen demand (COD), total dissolved solids (TDS), total nitrogen (TN) and turbidity. The optimal removal of COD, TDS, TN and turbidity in the current study was 56.47, 83.00, 52.12, and 79.98% for Salvinia molesta as well as 48.81, 24.00, 13.56 and 19.89% for water hyacinth.