Surface water pollution is mainly due to large urbanization, agricultural waste and discharges of production. The purpose of this study is to evaluate the pollutant parameters of surface waters effluents contaminated by synthetic detergents and organic chemical substances. During the study were analyzed physico-chemical parameters such as: Phosphate ion (PO₄³⁻), Total Phosphate (TP), Sodium tripolyphosphate (Na5P3O10), Sodium perborate (NaBO3 n H2O ), Ammonium (NH4+), Nitrate (NO⁻₃.), Nitrite (NO2−), Water temp. (0C), Hydrogen ion concentration (pH). The correlation between the source water and the current level of pollution of this river was measured in four locations:(Prevalla L1; Reqane L2; City park L3; Vlashnje L4) along the surface course of the Lumbardhi River in Prizren. From the results of the study for both time periods, the chemical parameters values of Phosphate ion (PO₄³⁻) for May, 2022 according to monitoring of physico-chemical parameters in Lumbardhi River in Prizren were 0,001. Value of Total Phosphate (TP) was 0.002, for Sodium tripolyphosphate (Na5P3O10). Water quality of the Lumbardhi river directly depends on the amount of flows in the river. Poor quality of the water is more during the month of October, when the amount of flows in the river is smaller. Location (L3) had higher pollution as a result of the discharge of urban sewage and city waste. Research has shown the presence of different forms of phosphorus that are higher in the (L2 and L3) locations.