Atmospheric Sedimentable Dust (ASD) pollution is a critical environmental problem in urban and peri-urban areas. This study evaluated the spatiotemporal dynamics of ASD and its relationship with vehicular flow and meteorology along the Jancao–La Esperanza road corridor (Huánuco). During 31 consecutive days, 10 sampling stations were monitored using the passive gravimetric method. Categorized vehicular flow was recorded through video surveillance, and meteorological variables were obtained from SENAMHI. The analysis integrated Spearman correlations, a lognormal generalized linear mixed model (GLMM), spatial IDW interpolation, and wind rose analysis. The highest cumulative daily deposition rate along the section occurred on May 17 (247.64 mg/cm²). The observational design, GLMM, and Spearman correlations demonstrated no statistically significant associations between the ASD deposition rate and fluctuations in vehicular flow or meteorological variables. Spatial variability among stations was negligible, whereas the sampling date explained the temporal fluctuations in the data. At the local level, station P-010 (northern sector) recorded the highest cumulative load (166.00 mg/cm²) and a daily median of 0.80 mg/cm²/day, associated with passive advection by NE–ENE winds and microlocal interception dynamics. It is concluded that ASD acts as background pollution governed by regional atmospheric dynamics rather than by local vehicular flow. This study provides unprecedented technical evidence for characterizing ASD deposition in inter-Andean valleys, offering a high-temporal-resolution monitoring scheme applicable to air quality management in peri-urban areas.