The research evaluated the synergy between natural coagulants (Moringa oleifera) and synthetic coagulants (aluminum sulfate) in the removal of solids from wastewater from slaughter centers. The physicochemical parameters (TSS, turbidity and color) were characterized. Samples were collected at the point of discharge, filtered and homogenized. The powder of M. oleifera was obtained after cleaning, drying, grinding, alcoholic extraction and activation with NaCl. A completely randomized design was applied with three factors (coagulant dose and pH), generating 12 treatments evaluated with a jug test, determining removal efficiency and solids generated. The slaughtering process in the Calceta slaughterhouse generates solid and liquid waste, especially in the bleeding, skinning and evisceration. The wastewater has 450 mg/L TSS and 319 PCU of color, exceeding the regulatory limits, while turbidity (23.54 NTU) remains within the permitted range. The treatments applied achieved removals of up to 90% in color, 85% in turbidity and 98.96% in SST, highlighting treatments 9, 11 and 12. The analysis of variance showed that the dose of the biocoagulant had a significant effect on the removal of color (p=0.0007) and total suspended solids (p=0.0005). Aluminum sulfate dose and pH were not significant. Overall, efficiencies reached up to 90% in color and nearly 99% in solids. The production of solids ranged between 60 - 80 grams depending on the treatment applied, demonstrating that this synergy contributes to the performance in the removal of solids.