The aim of the article is to investigate the water quality in the Prut River, which tends to tourist destinations, and to establish the interdependence of the water pollution index with the number of tourists visited in the Yaremche Tourist Cluster. The article scientifically proves the indirect influence of tourist flow on water quality in the Prut River. Water samples from the Prut River were taken, such as pH, temperature, nitrates and nitrites, phosphates, ammonium and mineralization were analyzed. Using membrane tests Sensafe in water samples, we determined the content of the following metals: Ni, Co, Zn, Cd, Hg, Fe. Based on the results, we calculated the water pollution index, which is 0.52. It is established that the water is clean. IZV is determined at each point of water withdrawal in the dynamics during 2016-2020, the interdependence of water quality of the Prut River with the number of visitors to the tourist destination. The forecast of the index of water pollution and tourist flow for 2021-2025 is carried out using the data received in the operating system Exel. It is proved that with the growth of tourists the water quality deteriorates, although it fluctuates within the norm.