The article highlights experimental and field studies of the scientific problem of increasing the yield of soybean seeds by optimizing the main elements of growing technology. Improved standards for the depletion of major biological nutrients during the formation of units in soybean crops make it possible to specify the standards of foliar fertilization to obtain the planned levels of yield and removal of these elements from the soil. The obtained results are of practical importance, as they contribute to optimizing the nutrition of soybean plants due to the use of foliar fertilizers Ecoline Legume. This helps to increase seed yield to the level of 2.0–2.5 tons per hectare. The researchers also conducted a generalization and analysis of scientific results in the field of soybean yield management through foliar feeding. In addition, scientific publications on the influence of liming, application of organic, mineral and microfertilizers on the physicochemical and agrochemical properties of the soil were analyzed. The cultivation of soybeans and the rational application of foliar fertilization are economically beneficial methods, and in this case, the use of foliar fertilization Ecoline Legume to approximately neutral reaction of the soil environment contributed to obtaining the highest levels of conditional net profit and profitability. This confirms the high energy efficiency of soybean cultivation